| Date | Opponent | Location | Time/Result | Record/MEAC | Game Story | |
| Nov. 9 | Cheyney State (Exhibition) | Memorial Hall | 68-31 DSU | |||
| Nov. 5 | Lincoln (Exhibition) | Memorial Hall | 79-24 DSU | Game Story | ||
| Nov. 18 | Florida Atlantic Classic vs. Monmouth |
Boca Raton, FL | 50-44 DSU | 1-0, 0-0 | Game Story | |
| Nov. 19 | Florida Atlantic Classic at Florida Atlantic |
Boca Raton, FL | 65-59 DSU | 2-0, 0-0 | Game Story | |
| Nov. 23 | Columbia | New York, NY | 62-61 DSU | 3-0, 0-0 | Game Story | |
| Nov. 30 | Kansas State | Manhattan, KS | 78-30 KSU | 3-1, 0-0 | Game Story | |
| Dec. 09 | Navy | Annapolis, MD | 53-45 DSU | 4-1, 0-0 | Game Story | |
| Dec. 11 | North Carolina State | Raleigh, NC | 76-58 NCSU | 4-2, 0-0 | Game Story | |
| Dec. 19 | Yale | Memorial Hall | 58-48 DSU | 5-2, 0-0 | Game Story | |
| Dec. 28 | Stony Brook | Stony Brook, NY | 70-59 SB | 5-3, 0-0 | Game Story | |
| Dec. 30 | Bucknell | Lewisburg, PA | 60-42 DSU | 6-3, 0-0 | Game Story | |
| Jan. 04 | ![]() |
Coppin State | Memorial Hall | 43-39 CSU | 6-4, 0-1 | Game Story |
| Jan. 07 | ![]() |
South Carolina State | Memorial Hall | 55-48 DSU | 7-4, 1-1 | Game Story |
| Jan. 09 | ![]() |
North Carolina A&T State | Memorial Hall | 50-49 NCAT | 7-5, 1-2 | Game Story |
| Jan. 14 | ![]() |
Howard | Washington, DC | 75-70 DSU | 8-5, 2-2 | Game Story |
| Jan. 16 | ![]() |
Maryland - Eastern Shore | Princess Anne, MD | 65-51 DSU | 9-5, 3-2 | Game Story |
| Jan. 21 | ![]() |
Hampton | Hampton, VA | 64-59 HAM | 9-6, 3-3 | Game Story |
| Jan. 23 | ![]() |
Norfolk State | Norfolk, VA | 65-49 DSU | 10-6, 4-3 | Game Story |
| Jan. 28 | ![]() |
Florida A&M | Memorial Hall | 55-48 DSU | 11-6, 5-3 | Game Story |
| Jan. 30 | ![]() |
Bethune-Cookman | Memorial Hall | 70-29 DSU | 12-6, 6-3 | Game Story |
| Feb. 04 | ![]() |
South Carolina State | Orangeburg, SC | 64-55 SCSU | 12-7, 6-4 | Game Story |
| Feb. 06 | ![]() |
North Carolina A&T State | Greensboro, NC | 80-65 DSU | 13-7, 7-4 | Game Story |
| Feb. 11 | ![]() |
Howard | Memorial Hall | 87-65 DSU | 14-7, 8-4 | Game Story |
| Feb. 13 | ![]() |
Maryland - Eastern Shore | Memorial Hall | 64-45 DSU | 15-7, 9-4 | Game Story |
| Feb. 18 | ![]() |
Hampton | Memorial Hall | 65-58 HU | 15-8, 9-5 | Game Story |
| Feb. 20 | ![]() |
Norfolk State | Memorial Hall | 75-40 DSU | 16-8, 10-5 | Game Story |
| Feb. 25 | ![]() |
Florida A&M | Tallahassee, FL | 65-50 DSU | 17-8, 11-5 | Game Story |
| Feb. 27 | ![]() |
Bethune-Cookman | Daytona Beach, FL | 48-47 DSU | 18-8, 12-5 | Game Story |
| Mar. 01 | ![]() |
Morgan State | Baltimore, MD | 61-43 DSU | 19-8, 13-5 | Game Story |
| Mar. 08 | MEAC Championship vs. Florida A&M |
Raleigh, NC | 55-44 DSU | 20-8, 13-5 | Game Story | |
| Mar. 10 | MEAC Championship vs. Maryland-Eastern Shore |
Raleigh, NC | 66-53 DSU | 21-8, 13-5 | Game Story | |
| Mar. 11 | MEAC Championship vs. Coppin State |
Raleigh, NC | 46-36 CSU | 21-9, 13-5 | Game Story |
Indicates
MEAC game. Home games in bold.