| Date | Opponent | Location | Time/Result | Record/MEAC | Game Story | |
| Nov. 19 | UCLA | Los Angeles, CA | 56-37 UCLA | 0-1, 0-0 | Game Story | |
| Nov. 21 | South Padre Island Invitational at Kent State |
Kent, OH | 65-56 DSU | 1-1, 0-0 | Game Story | |
| Nov. 22 | South Padre Island Invitational at Rutgers |
Piscataway, NJ | 49-42 Rutgers | 1-2, 0-0 | Game Story | |
| Nov. 25 | South Padre Island Invitational vs. Austin Peay State |
South Padre Island, TX | 57-51 APSU | 1-3, 0-0 | Game Story | |
| Nov. 26 | South Padre Island Invitational vs. Wichita State |
South Padre Island, TX | 62-44 WSU | 1-4, 0-0 | Game Story | |
| Dec. 03 | Northwestern | Evanston, IL | 61-54 NU | 1-5, 0-0 | Game Story | |
| Dec. 05 | Jacksonville State | Jacksonville, AL | 73-62 DSU | 2-5, 0-0 | Game Story | |
| Dec. 07 | Michigan | Ann Arbor, MI | 69-49 UM | 2-6, 0-0 | Game Story | |
| Dec. 17 | Bradley | Peoria, IL | 68-46 BU | 2-7, 0-0 | Game Story | |
| Dec. 22 | Marquette | Milwaukee, WI | 60-48 MU | 2-8, 0-0 | Game Story | |
| Dec. 28 | Maryland | College Park, MD | 68-54 UM | 2-9, 0-0 | Game Story | |
| Dec. 30 | Buffalo | Memorial Hall | 56-51 UB | 2-10, 0-0 | Game Story | |
| Jan. 04 |  |
Coppin State | Memorial Hall | 58-54 DSU | 3-10, 1-0 | Game Story |
| Jan. 07 | |
South Carolina State | Memorial Hall | 66-60 DSU | 4-10, 2-0 | Game Story |
| Jan. 09 | |
North Carolina A&T State | Memorial Hall | 56-52 DSU | 5-10, 3-0 | Game Story |
| Jan. 14 | |
Howard | Washington, DC | 60-46 DSU | 6-10, 4-0 | Game Story |
| Jan. 16 | |
Maryland - Eastern Shore | Princess Anne, MD | 70-67 DSU | 7-10, 5-0 | Game Story |
| Jan. 21 | |
Hampton | Hampton, VA | 61-58 DSU | 8-10, 6-0 | Game Story |
| Jan. 23 | |
Norfolk State | Norfolk, VA | 57-54 DSU | 9-10, 7-0 | Game Story |
| Jan. 28 | |
Florida A&M | Memorial Hall | 61-50 DSU | 10-10, 8-0 | Game Story |
| Jan. 30 | |
Bethune-Cookman | Memorial Hall | 68-58 DSU | 11-10, 9-0 | Game Story |
| Feb. 03 | |
South Carolina State | Orangeburg, SC | 63-51 SCSU | 11-11, 9-1 | Game Story |
| Feb. 06 | |
North Carolina A&T State | Greensboro, NC | 48-45 DSU | 12-11, 10-1 | Game Story |
| Feb. 11 | |
Howard | Memorial Hall | 59-50 DSU | 13-11, 11-1 | Game Story |
| Feb. 13 | |
Maryland - Eastern Shore | Memorial Hall | 64-48 DSU | 14-11, 12-1 | Game Story |
| Feb. 18 | |
Hampton | Memorial Hall | 88-77 DSU | 15-11, 13-1 | Game Story |
| Feb. 20 | |
Norfolk State | Memorial Hall | 59-50 DSU
| 16-11, 14-1 |
Game Story |
|
| Feb. 25 | |
Florida A&M | Tallahassee, FL | 61-58 DSU | 17-11, 15-1 | Game Story |
| Feb. 27 | |
Bethune-Cookman | Daytona Beach, FL | 72-71 BCC | 17-12, 15-2 | Game Story |
| Mar. 01 | |
Morgan State | Baltimore, MD | 52-43 DSU | 18-12, 16-2 | Game Story |
| Mar. 08 | MEAC Championship vs. Howard |
Raleigh, NC | 59-47 DSU | 19-12, 16-2 | Game Story | |
| Mar. 10 | MEAC Championship vs. South Carolina State |
Raleigh, NC | 63-51 DSU | 20-12, 16-2 | Game Story | |
| Mar. 11 | MEAC Championship vs. Hampton |
Raleigh, NC | 60-56 HU | 20-13, 16-2 | Game Story | |
| Mar. 14 | NIT vs. Northern Arizona | Flagstaff, AZ | 58-53 DSU | 21-13, 16-2 | Game Story | |
| Mar. 17 | NIT vs. Louisville | Louisville, KY | 71-54 UL | 21-14, 16-2 | Game Story |
Indicates
MEAC game. Home games in bold.